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Dr Radha Kodiappan


Position : Senior Lecturer, Head of Student Progress Committee

Qualifications

  • PhD, MSc. (Human Genetics),
  • BSc. Hons. (Microbiology)
  • Certification in Training (License TTT/18189)

Alma Mater : Universiti Putra Malaysia & Pembangunan Sumber Manusia Berhad

Subjects Taught 

  • Molecular Medicine (Genetics)
  • Fundamentals in Biomedicine (Biochemistry, Cell Biology & Immunology)
  • Bioinformatics

Interests : Watercolour paintings & zentangle

Email : [email protected]

Phone (office) : +60 3-8941 7661

Dr Radha Kodiappan is an experienced and dedicated educator and researcher, who is passionate about giving her students the best possible education and experience in life.

Over the past 7 years, she has enthusiastically and diligently taught the genetics, biochemistry, cell biology and immunology components of the Junior Cycle RCSI Undergraduate Medical Programme. She is fundamentally committed to good practise, actively engaged in continues learning and constantly strives towards exceeding goals and expectations.

Dr Radha enjoys working in a busy environment and relishes the challenge of managing a diverse workload.  She has served as the Module Facilitator for the Molecular Medicine module for the past 6 years, where she ensures the seamless delivery of the module throughout the semester. She also chair the Student Progress Committee (PU-RCSI) that monitors students’ academic progress and suggests remedial courses of action for poorly performing students. Dr Radha also serve on several other committees including Perdana University Research Committee (PU), PU-RCSI Medical Faculty Board (PU-RCSI), PU-RCSI Exam Board (PU-RCSI/Dublin), Junior Cycle Committee (PU-RCSI), Junior Cycle Module Board (PU-RCSI/Dublin/Bahrain), and Student Support and Mentor Programme (PU-RCSI).

Research Interests

  1. Keywords:

Cancer, Genetics, Epigenetics, Cancer Stem Cells, microRNAs

  1. Short description

Dr Radha Kodiappan is a molecular geneticist and her main research interest is in cancer epigenetics. Her PhD research focused on identifying microRNAs that regulate the expression of histone-modifying enzymes in invasive bladder cancer. She has won numerous awards for this work and the proceedings from this study was published in the prestigious Journal of Cancer Research (2014; 74(19), P5213; impact factor 9.329). Her Master’s degree was also in the field of genetics, where she worked mainly on the genetic factors of drug addiction, specifically identifying genetic mutations that contribute to addictive traits in the Malaysian population. The proceedings this work was published in the European Journal of Human Genetics – Nature (2009; 17(2): 222, P08.26; impact factor 4.58). Currently, she is also involved in community health studies which are focused on women health.

Dr Radha has had extensive training in applying for and managing external research grants since 2006, when she was the co-researcher for two studies funded by the E-Science Grant (MOSTI; 2006; RM260,000) and the High Impact Research Grant (UM-MOHE; 2012; RM200,000). She secured the first external research grant (FRGS) for Perdana University in 2013 (MOHE; RM149,000), as the principal investigator and she was a co-researcher for another FRGS grant (MOHE; RM195,00) in this University. She have submitted another 2 FRGS grant applications in the recent cycle, 2018.

In terms of student supervision, during her PhD candidature, Dr Radha has mentored 5 postgraduates in Universiti Putra Malaysia. She has also supervised 25 PU-RCSI undergraduate students during their Student Selected Component (SSC) module and summer research, and co-supervised 5 postgraduates from PUGSOM during their scholarly concentration.

Clubs and Associations

  • KRSMC, Perdana University (Member),
  • Genetic Society of Malaysia (Honorary Assistant Secretary (2017-2019), PGM0455),
  • Young Scientist Network-Academy of Sciences Malaysia (YSN-ASM)(Affiliate Member).

Publications

  1.     Age Differences in Women’s Perception of Access to Healthcare, Communication with Healthcare Providers and Usefulness of Health Information Sources. Kodiappan R, Hsia YK, Azim DHF, Singh SK. Malaysian J Public Health Med. 2018 Jul; 18(Suppl. 2): 44-45, FHOP009. ISSN: 1675-0306.
  2.     Adult Stem Cell Therapy in Liver Cirrhosis Management: Current Practices and Future Perspectives. Gounder SS, Kodiappan R, Soon Choy C, Veerakumarasivam A, Subraman B. Int J Stem Cell Res Ther. 2017 (4)049:1-10. doi: 10.23937/2469-570X/1410049. Review.
  3.     Human Mesenchymal Stromal Cells Modulate T-Cell Immune Response Via Transcriptomic Regulation. Vellasamy S, Tong CK, Azhar NA, Kodiappan R, Chan SC, Veerakumarasivam A, Ramasamy R. Cytotherapy. 2016 Oct;18(10):1270-83. doi: 10.1016/j.jcyt.2016.06.017. Epub 2016 Aug 16.
  4.     MicroRNA-mediated Loss of KDM5B Expression Leads to Suppression of the Malignant Bladder Cancer Phenotype. Veerakumarasivam A, Kodiappan R, Chan SC, Razack AHA, Ong TA. Cancer Research. 2014 Oct;74(19): P5213. doi: 10.1158/15387445. (PhD Research).
  5.     MicroRNA: Epigenetic Modifiers in Regenerative Medicine. Kodiappan R, Tan KS, Lai JY, Chin FW, Chan SC and Veerakumarasivam A. Regenerative Res. 2014 June;3(1):29-40. e-ISSN: 2232-0822. Review.

6.     Mutation Analysis of the Human Fatty Acid Hydrolase Gene and the Risk of Drug Addiction. Kodiappan R, Rosli R, Rampal L, Sidik SM, Hwa LK. European Journal of Human Genetics. 2009 May;17(2): 222, P08.26.

Awards and Accomplishments

Fellowship

Graduate Research Fellowship (Ph.D), UPM: 2010-2011

Awards

  • Silver Medal, Invention, Research & Innovation Exhibition 2006, 2007, 2009 Universiti Putra Malaysia
  • First Prize for PhD Category (Faculty Level), 3 Minutes Thesis Competition 2013, Universiti Putra Malaysia
  • Gold and Bronze Medal for Cancer Research Poster Competition in conjunction with Cancer Awareness Carnival 2014, Universiti Putra Malaysia
  • EURAEXCESS Science Slam Malaysia 2015 Award, Ministry of Science, Technology and Innovation (MOSTI)
  • E-Science Universiti Putra Malaysia Research Grant from MOSTI as co-researcher in single nucleotide polymorphisms of the human fatty acid amide hydrolase gene and its association with the risk of drug addiction in Malaysian subjects (2006-2009)
  • University Malaya High Impact Research Grant by MOHE as co-researcher in large-scale profiling of cancer/testis antigens and the delineation of miRNA-mediated reversal of CTA-associated aberrant demethylation in urothelial cell carcinoma (2012-2014)
  • Fundamental Research Grant Scheme by MOHE as principle investigator in in-vitro characterization of the functional role of miR-137 in regulating KDM5B and bladder cancer stemness (2013-2016) and as co-investigator in Deciphering the Aggressive Bladder Cancer Stem Cell Phenotype (2015-2018)

Collaborations     

  • Prof Abimanyu Veerakumarasivam (Sunway University)
  • Prof Rozita Rosli, Dr Ling King Hwa (University Putra Malaysia)
  • Assoc. Prof. Dr. Chan Soon Choy
  • Dr Wendy Yeo
  • Ms Darlina Hani
  • Dr Sangeeta Kaur
  • Prof Manoj
  • Assoc Prof Dr Jeevan Shetty

Dr Radha Kodiappan is an experienced and dedicated educator and researcher, who is passionate about giving her students the best possible education and experience in life.

Over the past 7 years, she has enthusiastically and diligently taught the genetics, biochemistry, cell biology and immunology components of the Junior Cycle RCSI Undergraduate Medical Programme. She is fundamentally committed to good practise, actively engaged in continues learning and constantly strives towards exceeding goals and expectations.

Dr Radha enjoys working in a busy environment and relishes the challenge of managing a diverse workload.  She has served as the Module Facilitator for the Molecular Medicine module for the past 6 years, where she ensures the seamless delivery of the module throughout the semester. She also chair the Student Progress Committee (PU-RCSI) that monitors students’ academic progress and suggests remedial courses of action for poorly performing students. Dr Radha also serve on several other committees including Perdana University Research Committee (PU), PU-RCSI Medical Faculty Board (PU-RCSI), PU-RCSI Exam Board (PU-RCSI/Dublin), Junior Cycle Committee (PU-RCSI), Junior Cycle Module Board (PU-RCSI/Dublin/Bahrain), and Student Support and Mentor Programme (PU-RCSI).

Research Interests

  1. Keywords:

Cancer, Genetics, Epigenetics, Cancer Stem Cells, microRNAs

  1. Short description

Dr Radha Kodiappan is a molecular geneticist and her main research interest is in cancer epigenetics. Her PhD research focused on identifying microRNAs that regulate the expression of histone-modifying enzymes in invasive bladder cancer. She has won numerous awards for this work and the proceedings from this study was published in the prestigious Journal of Cancer Research (2014; 74(19), P5213; impact factor 9.329). Her Master’s degree was also in the field of genetics, where she worked mainly on the genetic factors of drug addiction, specifically identifying genetic mutations that contribute to addictive traits in the Malaysian population. The proceedings this work was published in the European Journal of Human Genetics – Nature (2009; 17(2): 222, P08.26; impact factor 4.58). Currently, she is also involved in community health studies which are focused on women health.

Dr Radha has had extensive training in applying for and managing external research grants since 2006, when she was the co-researcher for two studies funded by the E-Science Grant (MOSTI; 2006; RM260,000) and the High Impact Research Grant (UM-MOHE; 2012; RM200,000). She secured the first external research grant (FRGS) for Perdana University in 2013 (MOHE; RM149,000), as the principal investigator and she was a co-researcher for another FRGS grant (MOHE; RM195,00) in this University. She have submitted another 2 FRGS grant applications in the recent cycle, 2018.

In terms of student supervision, during her PhD candidature, Dr Radha has mentored 5 postgraduates in Universiti Putra Malaysia. She has also supervised 25 PU-RCSI undergraduate students during their Student Selected Component (SSC) module and summer research, and co-supervised 5 postgraduates from PUGSOM during their scholarly concentration.

Publications

  1.     Age Differences in Women’s Perception of Access to Healthcare, Communication with Healthcare Providers and Usefulness of Health Information Sources. Kodiappan R, Hsia YK, Azim DHF, Singh SK. Malaysian J Public Health Med. 2018 Jul; 18(Suppl. 2): 44-45, FHOP009. ISSN: 1675-0306.
  2.     Adult Stem Cell Therapy in Liver Cirrhosis Management: Current Practices and Future Perspectives. Gounder SS, Kodiappan R, Soon Choy C, Veerakumarasivam A, Subraman B. Int J Stem Cell Res Ther. 2017 (4)049:1-10. doi: 10.23937/2469-570X/1410049. Review.
  3.     Human Mesenchymal Stromal Cells Modulate T-Cell Immune Response Via Transcriptomic Regulation. Vellasamy S, Tong CK, Azhar NA, Kodiappan R, Chan SC, Veerakumarasivam A, Ramasamy R. Cytotherapy. 2016 Oct;18(10):1270-83. doi: 10.1016/j.jcyt.2016.06.017. Epub 2016 Aug 16.
  4.     MicroRNA-mediated Loss of KDM5B Expression Leads to Suppression of the Malignant Bladder Cancer Phenotype. Veerakumarasivam A, Kodiappan R, Chan SC, Razack AHA, Ong TA. Cancer Research. 2014 Oct;74(19): P5213. doi: 10.1158/15387445. (PhD Research).
  5.     MicroRNA: Epigenetic Modifiers in Regenerative Medicine. Kodiappan R, Tan KS, Lai JY, Chin FW, Chan SC and Veerakumarasivam A. Regenerative Res. 2014 June;3(1):29-40. e-ISSN: 2232-0822. Review.

6.     Mutation Analysis of the Human Fatty Acid Hydrolase Gene and the Risk of Drug Addiction. Kodiappan R, Rosli R, Rampal L, Sidik SM, Hwa LK. European Journal of Human Genetics. 2009 May;17(2): 222, P08.26.

Awards and Accomplishments

Fellowship

Graduate Research Fellowship (Ph.D), UPM: 2010-2011

Awards

  • Silver Medal, Invention, Research & Innovation Exhibition 2006, 2007, 2009 Universiti Putra Malaysia
  • First Prize for PhD Category (Faculty Level), 3 Minutes Thesis Competition 2013, Universiti Putra Malaysia
  • Gold and Bronze Medal for Cancer Research Poster Competition in conjunction with Cancer Awareness Carnival 2014, Universiti Putra Malaysia
  • EURAEXCESS Science Slam Malaysia 2015 Award, Ministry of Science, Technology and Innovation (MOSTI)
  • E-Science Universiti Putra Malaysia Research Grant from MOSTI as co-researcher in single nucleotide polymorphisms of the human fatty acid amide hydrolase gene and its association with the risk of drug addiction in Malaysian subjects (2006-2009)
  • University Malaya High Impact Research Grant by MOHE as co-researcher in large-scale profiling of cancer/testis antigens and the delineation of miRNA-mediated reversal of CTA-associated aberrant demethylation in urothelial cell carcinoma (2012-2014)
  • Fundamental Research Grant Scheme by MOHE as principle investigator in in-vitro characterization of the functional role of miR-137 in regulating KDM5B and bladder cancer stemness (2013-2016) and as co-investigator in Deciphering the Aggressive Bladder Cancer Stem Cell Phenotype (2015-2018)

Clubs and Associations

  • KRSMC, Perdana University (Member),
  • Genetic Society of Malaysia (Honorary Assistant Secretary (2017-2019), PGM0455),
  • Young Scientist Network-Academy of Sciences Malaysia (YSN-ASM)(Affiliate Member).

Collaborations 

  • Prof Abimanyu Veerakumarasivam (Sunway University)
  • Prof Rozita Rosli, Dr Ling King Hwa (University Putra Malaysia)
  • Assoc. Prof. Dr. Chan Soon Choy
  • Dr Wendy Yeo
  • Ms Darlina Hani
  • Dr Sangeeta Kaur
  • Prof Manoj
  • Assoc Prof Dr Jeevan Shetty