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Public Lecture on Molecular Control of Vertebrate Retinal Development and Human Diseases

Date : 30 November 2017
Venue : Auditorium 5, Perdana University, Serdang Campus
Time : 11.00am – 12.00pm

Free Admission


Abstract

The neural retina is developmentally a part of the central nervous system (CNS) and known as a good model system to study the molecular basis of CNS development. The retina was previously thought as a tissue just to receive light, convert it into electrical signals, and transmit them to the brain. However, it has gradually become known that visual information processing, including detection of light-dark contrast, movement, and color, begins from the retina. Thus, the retina is called an approachable part of the brain. We have been studying molecular mechanisms underlying vertebrate retinal development and maintenance in the viewpoints of cell differentiation, neuronal circuit formation, and retinal degeneration associated with human diseases, including retinitis pigmentosa, ciliopathy, night blindness, muscular dystrophy, and cancer-associated retinopathy. I will briefly review my research and introduce our recent studies.

 

Speaker

Professor T Furukawa MD, PhD  is a distinguished Professor and Chair of Laboratory and Developmental Biology, Division of Integrated Protein Functions, Institute of Protein Research, Osaka University, Japan. He is one of the outstanding scientists in Japan and abroad. He is a leading scientist in the field of opthalmology for his new discoveries in molecular bases of  photoreceptors. He received his MD from Osaka University and a PhD from Kyoto University. He worked as a research associate at the Department of  Medical Chemistry, Kyoto University with renowned Prof. Honjo before he went  to the Dr. Connie Cepko lab, in Harvard University as a post-doc and became Assistant Professor of the  Center for Developmental Biology and Biochemistry at the University Texas South Western  Medical Center at Dallas, USA. He then returned to Japan and took the position of Head of Department of . Developmental Biology at the Osaka Bioscience Institute.  He served as an Adjunct Professor  at various universities in Japan such as the Kyoto University School of Medicine, Osaka University School of Medicine, Osaka University Graduate School of Frontier Biosciences. He became l Professor  at the Osaka University, Institute for Protein Research in 2012.

His research interests include:-

I. Molecular mechanism of synapse formation in the retina
II. Mechanisms of cell fate determination of the vertebrate retina
III. Elucidation of functional roles of microRNAs (miRNAs) in CNS development
IV. Mechanisms of cilia formation using molecular genetics of zebrafish
V. Generation of KO/transgenic mice and analysis of visual function of genetically engineered mice

http://www.protein.osaka-u.ac.jp/furukawa_lab/english.html

 

Awards

He was awarded many prestigious titles, awards and prizes as follows from local as well as international bodies for his outstanding contribution in medical science.

  1. Pfizer opthalmic award Japan
  2. Baelz prize
  3. Japan society for promotion of science prize
  4. Osaka prize
  5. Osaka University President Awards
  6. MEXT Science and Technology Award for Excellent Research
  7. Osaka University distinguished Professor

 

Publications

He had published more than 100 research papers in high ranking prestigious journals such as Nature, Neuron, Nature Immunology, Nat Neurosci, Nat Genet, Nat Cell Biol , Science, PNAS, J Mol Bichem, J Neurosci , Cell Biol, Hum Mol Genet, Mol Cell Biol, EMBO and  Cell,  etc… with many citations.

 

Books

Editor

He was an editor of a book published in 2014 by Springer, “Vertebrate Photoreceptors Functional Molecular Bases”.

Book Chapter

He has written 2 book chapters, Pathgologies of Calcium Channels “TRPM1 and Congenital Stationary Night Blindness”  in 2012 by Springer and Micro-RNA let-7 in Role in Human Diseases and Drug Discovery published in 2012 by Nova Science Publishers.

Date

November 30

Time

11:00 am - 12:00 pm
Category

Organizer

Perdana University
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